Triethanolamine Stabilization of Methotrexate-β-Cyclodextrin Interactions in Ternary Complexes
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چکیده
منابع مشابه
Triethanolamine Stabilization of Methotrexate-β-Cyclodextrin Interactions in Ternary Complexes
The interaction of methotrexate (MTX) with beta-cyclodextrin (β-CD) in the presence of triethanolamine (TEA) was investigated with the aim to elucidate the mechanism whereby self-assembly cyclodextrin systems work in association with this third component. Solubility diagram studies showed synergic increment of the MTX solubility to be about thirty-fold. Experiments using 2D ROESY and molecular ...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2014
ISSN: 1422-0067
DOI: 10.3390/ijms150917077